Roxies

Oxycodone, sold under the brand name Roxicodone and OxyContin (which is the extended-release form) among others, is a semi-synthetic opioid used medically for the treatment of moderate to severe pain. It is highly addictive and is a commonly abused drug. It is usually taken by mouth, and is available in immediate-release and controlled-release formulations. Onset of pain relief typically begins within fifteen minutes and lasts for up to six hours with the immediate-release formulation. In the United Kingdom, it is available by injection. Combination products are also available with paracetamol (acetaminophen), ibuprofen, naloxone, naltrexone, and aspirin. Common side effects include euphoria, constipation, nausea, vomiting, loss of appetite, drowsiness, dizziness, itching, dry mouth, and sweating. Side effects may also include addiction and dependence, substance abuse, irritability, depression or mania, delirium, hallucinations, hypoventilation, gastroparesis, bradycardia, and hypotension. Those allergic to codeine may also be allergic to oxycodone. Use of oxycodone in early pregnancy appears relatively safe. Opioid withdrawal may occur if rapidly stopped. Oxycodone acts by activating the μ-opioid receptor. When taken by mouth, it has roughly 1.5 times the effect of the equivalent amount of morphine. Oxycodone was originally produced from the opium poppy opiate alkaloid thebaine in 1916 in Germany. One year later, it was used medically for the first time in Germany in 1917. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2022, it was the 60th most commonly prescribed medication in the United States, with more than 11 million prescriptions. A number of abuse-deterrent formulations are available, such as in combination with naloxone or naltrexone.

King Snake - 2025-06-12T00:00:00.000000Z

Need No One - 2025-06-10T00:00:00.000000Z

OMG - 2025-06-10T00:00:00.000000Z

Hold On - 2025-06-09T00:00:00.000000Z

Model Hoes - 2025-06-09T00:00:00.000000Z

Jugg Time - 2025-06-05T00:00:00.000000Z

Line - 2025-06-05T00:00:00.000000Z

Toxic - 2025-06-05T00:00:00.000000Z

Bone - 2025-05-28T00:00:00.000000Z

Couple - 2025-05-26T00:00:00.000000Z

April Fools - 2025-05-25T00:00:00.000000Z

Juug Shit - 2025-05-25T00:00:00.000000Z

Off the Xan - 2025-05-25T00:00:00.000000Z

Fasho 2 - 2025-05-24T00:00:00.000000Z

Meth - 2025-05-24T00:00:00.000000Z

Rest - 2025-05-24T00:00:00.000000Z

Still - 2025-05-24T00:00:00.000000Z

Show the Way - 2025-05-23T00:00:00.000000Z

Net - 2025-05-21T00:00:00.000000Z