ME2
ME2 or ME-2 may refer to:
ME2 (gene)
"Me²", an episode of the British sitcom Red Dwarf
Mass Effect 2, a video game released for Microsoft Windows and Xbox 360 in 2010, and for PlayStation 3 in 2011
Maine's 2nd congressional district
U.S. Route 2 in Maine
Me1 vs Me2 Snooker with Richard Herring
Me Two, French film
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